Andrew D. McCulloch, Ph.D.

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Professor and Jacobs Distinguished Scholar
Department of Bioengineering
University of California San Diego
9500 Gilman Drive
La Jolla, CA
92093-0412

Email: <amcculloch AT ucsd DOT edu>

Dr. Andrew McCulloch is Professor of Bioengineering and Jacobs School Distinguished Scholar at the University of California San Diego, where he joined the faculty in 1987. He is member of the UCSD Institute for Engineering in Medicine, the California Institute for Telecommunications and Information Technology, a Senior Fellow of the San Diego Supercomputer Center, and a member of the UCSD Center for Research on Biological Systems. Dr. McCulloch is a Principal Investigator of the National Biomedical Computation Resource and Co-Director of the Cardiac Biomedical Science and Engineering Center at UCSD. He served as Vice Chair of the Bioengineering Department from 2002 to 2005 and Chair from 2005 to 2008. Dr. McCulloch is Director of the HHMI-NIBIB Interfaces Graduate Training Program and the accompanying UCSD Interdisciplinary Ph.D. Specialization in Multi-SCale Biology.

Dr. McCulloch was educated at the University of Auckland, New Zealand in Engineering Science and Physiology receiving his Ph.D. in 1986. Dr. McCulloch was an NSF Presidential Young Investigator and is a Fellow of the American Institute for Medical and Biological Engineering. He has served on the Board of Directors of the Bio-Medical Engineering Society, and is currently Associate Editor of the Medical and Biological Engineering and Computing and PLoS Computational Biology and co-Editor-in-Chief of Drug Discovery Today: Disease Models. He is on the editorial boards of the American Journal of Physiology: Heart and Circulatory Physiology and Computer Methods in Biomechanics and Biomedical Engineering and Cellular and Molecular Bioengineering. Recently, he has given the Konrad Witzig Memorial Lecture and the Donald Wassenberg Memorial Lecture.

Dr. McCulloch’s lab uses experimental and computational models to investigate the relationships between the cellular and extracellular structure of cardiac muscle and the electrical and mechanical function of the whole heart during ventricular remodeling, and arrhythmia. Dr. McCulloch is a PI on the NCRR-supported National Biomedical Computation Resource, and has grants from the NHLBI, NSF and UC Discovery on cardiac tissue engineering, ventricular biomechanics, signaling pathways in cardiac hypertrophy and failure, cardiac electromechanical interactions, and computational cardiac biology.

Dr. McCulloch co-founded Insilicomed in 2000.

Selected Presentations

Multi-Scale Modeling of the Heart, Monash University eSeminar, September 4th, 2008
Lecture on Cardiac Modeling Methods, Case Western, Nov 29th, 2007
Departmental Overview, UCSD, June 18th, 2007
US National Committee on Biomechanics, Keystone, CO, June 19th, 2007
Departmental Overview, UCSD, November 27th, 2007
ISCE '07 Meeting, Cancun, April 23rd, 2007
IMAG Consortium Meeting, April 11-12th, 2007

Slides and Movies

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Cardiac Muscle Fiber Pattern
Automated Measurement of Cardiac Function in the Fruit Fly Heart
MRI in a mouse heart
Tagged MRI in a Patient with Heart Failure
Beating Heart cells Derived from Human Stem Cells